Number Т. 9, № 4 (36) 2019

A ground of application of platinum-based therapy in patients with triple-negative breast cancer

Yatsenko L.D.

Summary. Aim of the literature review is analysis of particularity of treatment of patients with triple-negative breast cancer using platinum-based therapy. Materials and methods. Results are analysed in 30 publications of the last years, devoted to the features of treatment of patients with triple-negative phenotype breast cancer. Results. Therapeutic possibilities at this variant of breast cancer are limited to the chemotherapy, efficiency of that remains lower compared with other types of breast cancer, that requires the search of the new modes of chemotherapy and markers of prognostication of effect. At planning of treatment of patients with triple-negative breast cancer has to be applied non-standard for breast cancer of regimens and modes of treatment, including by platinum-based therapy. Conclusions. At the same time, today there is not enough of data to recommend platinum as standard chemotherapy of patients with triple-negative breast cancer that stipulates the necessity of further deep researches.
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