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Pathogenetic basis for the classification and diagnosis of large B-cell lymphomas. Message I: DLBCL NOS, PMBL, HGBL (review)Summary. The review focuses on current data on genetic lesions and traits that serve as the basis for the diagnosis of diffuse large B-cell lymphoma, not otherwise specified (DLBCL NOS), primary mediastinal (thymic) large B-cell lymphoma (PMBL) and high-grade B-cell lymphoma (HGBL). These lymphomas, which are included in the group of mature neoplasms from large B cells, are characterized by both general and specific properties, the ratio of which serves as diagnostic criteria.
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