Pathogenetic basis for the classification and diagnosis of large B-cell lymphomas. Message I: DLBCL NOS, PMBL, HGBL (review)

Grabovoy A.N.1, Antonyuk S.A.2

Summary. The review focuses on current data on genetic lesions and traits that serve as the basis for the diagnosis of diffuse large B-cell lymphoma, not otherwise specified (DLBCL NOS), primary mediastinal (thymic) large B-cell lymphoma (PMBL) and high-grade B-cell lymphoma (HGBL). These lymphomas, which are included in the group of mature neoplasms from large B cells, are characterized by both general and specific properties, the ratio of which serves as diagnostic criteria.
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