Rhabdomyosarcoma of the larynx in adults. Review of the literature. Clinical reports. The case of a combination of rhabdomyosarcoma of the larynx and squamous cell carcinoma of the larynx

Fedorov D.Y.1, Yarynich К.V. 2, Yarynich V.I. 2

Summary. Rhabdomyosarcoma of the larynx is an extremely rare disease. Till now, only about 70 cases of rhabdomyosarcoma of the larynx, including the adult population — 39 cases have been described in the literature. There is very little information about the clinical presentation and course of rhabdomyosarcoma of the larynx. The article presents a review of the literature and our own observations of the disease. In our hospital, were treated 4 patients with rhabdomyosarcoma of the larynx. 3 of them had referred to our hospital for the first time, one has previously received radiation therapy for cancer of the larynx. In the analysis of the literature we found no reports of combined rhabdomyosarcoma of the larynx and squamous cell carcinoma of the larynx. All patients received surgical treatment, one received postoperative radiation therapy. The analysis of the literature data and our observations allowed us to conclude that the relatively favorable prognosis of laryngeal rhabdomyosarcoma in adults, given the possibility of early detection of disease, absence of regional and distant metastases in most cases, the possibility of radical surgical treatment.
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