Number Т. 10, № 3-4 (39-40)

NOTCH1 mutations in pathogenesis of chronic lymphocytic leukemia

Kryachok I.A.

Summary. The paper presented the modern data of influence NOTCH1 gene’s mutations on development of chronic lymphocytic leukemia: their frequencies, methods of detection, associations with clinical data, prognostic significance and approaches to the therapy of patients with NOTCH1 mutations.
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