Remifentanil is an effective anesthetic in modern anesthesiology and intensive care

Lisnyi I.I., Zakalska K.A.

Summary. The article is devoted to the possibilities of using remifentanil in anesthetic practice. Due to its pharmacological properties, this ultra-short-acting opioid allows achieving the maximum effect within 1–2 minutes, while the drug itself is rapidly hydrolyzed by nonspecific esterases. It provides good analgesia and sedation. It can be used in combination with other drugs for general anesthesia, in particular propofol, reducing the target concentration of the latter. Unlike morphine-based opioids, remifentanil has been shown to cause fewer hemodynamic side effects. An extensive database for the clinical use of remifentanil in intensive care, as well as in various areas of surgery, including neuro- and cardiac surgery, gynecology, etc. has been created based on numerous studies conducted in many countries.

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