Clinical case of the coexistence of lymphoproliferative and myeloprolipherative neoplasms in three patients
Summary. We report three clinical cases with coexistence of myeloproliferative and lymphoproliferative neoplasms in the same patients, which is uncommon finding for clinicist. All patients with myeloproliferative and lymphoproliferative neoplasms were diagnosed concomitantly; none of the patients have received any treatment prior to the survey. It is unclear whether there is a pathogenetic link between the myeloproliferative and lymphoproliferative diseases being probably the result of genetical mutations which occured in distinct precursors cells. The aim of this article is to present clinical cases and overview of modern literature in order to complete understanding of this kind of associations that in future will help to develop treatment protocols for these patients.
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