Immunotherapy of advanced melanoma

Kukushkina M.M., Korovin S., Kukushkina S.М., Palivets A., Ostafiichuk V., Diedkov A.G.

Summary. A breakthrough in cancer immunotherapy that has occurred in recent years is associated with understanding of interaction mechanisms between tumor and immune system, features of T-cell regulation and the creation of drugs selectively acting on components of this process. Skin melanoma is one of the most perspective malignancies for immunotherapy due to the high tumor immunogenicity and mutational load.
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