Modern methods of complex and personalized treatment of stomach cancer (literature review)

Колеснік О.П. , Левик О.М., Каджоян А.В., Кузьменко В.О., Cherniavskyi D.Y.

Summary. Summary. Today, stomach cancer is one of the most topical problems of modern oncology. According to the morbidity and mortality rates data of the National Cancer Register, gastric cancer takes 4th place (7.1%) among men and 8th place (4.2%) among women. According to the literature, the overall 5-year survival rate for resectable gastric cancer is approximately 53.5%, so the problem of choosing the right treatment tactics is extremely relevant. According to international recommendations, several treatment options are used as therapy for patients with resectable gastric cancer of the IB–III stages: neoadjuvant chemotherapy or neoadjuvant chemotherapy + radiation therapy followed by surgical treatment; adjuvant chemotherapy or adjuvant chemotherapy + radiation therapy after surgery; perioperative chemotherapy consisting of neoadjuvant chemotherapy and adjuvant chemotherapy. This article analyzes the results of clinical trials, the main purpose of which was to establish the most effective approach to the treatment of gastric cancer of IB–III stages by combining various treatment methods. Purpose: a review of specialized scientific literature to identify the most effective approach for the treatment of patients with gastric cancer of IB–III stages.

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