The lymph node assessment in treatment of endometrial cancer. The state of the problem

Bubliieva O., Svintsitsky V., Nespryadko S., Tsip N., Kopetskyi V., Krotevich M., Leonova N., Movchan O.

Summary. Endometrial cancer holds the third place in the structure of malignancies in Ukraine (9.6%) among all nosology forms of cancer. Pelvic and para-aortic lymph nodes dissection (LND) belongs to the methods for assessment of lymphatic nodes status. Nevertheless, trials conducted earlier show the absence of LND influence on the survival of patients with EC. Logical alternative might be a sentinel lymph node mapping (SLNM) by use of indocyanine green (ICG) followed by the biopsy which allows evaluating the status of lymphatic nodes with the least resort to radical surgery. Our prospective, randomized, non-inferiority study is multi-center clinical trial goaled at comparing the PFS in women with EC from the intermediate as well as high-intermediate risk groups, who had been performed SLN biopsy and systemic lymphadenectomy (pelvic and para-aortic lymph nodes dissection).

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