Number Т. 10, № 1-2 (37-38) 2020

Clinical significance of serum concentrations SCC antigen as a tumor marker in patients with cervical cancer

Vorobyova L.I., Goncharuk I.V.

Summary. We revealed an increase of tumor marker squamous cell carcinoma antigen concentration in serum in 60,4% of patients with stage IB–III squamous cell cervical cancer. Its diagnostical sensitivity rose from 7,8% (stage I) to 77,8% (stage III). We showed that patients with primary cervical cancer with metastases in regional lymph nodes squamous cell carcinoma antigen concentration is significantly higher (5,6+1,4 ng/ml), than in the group of patients without metastases (2,3+0,3 ng/ml) (р<0,05). 88,6% patients with cervical cancer recurrences showed increase of squamous cell carcinoma antigen concentration in serum with the mean value of 19,4+3,7 ng/ml (with individual oscillations limited by 0,5–70,0 ng/ml), what pointed on suitability of its usage as a marker of squamous cell cancer recurrence process.
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