Neoadjuvant chemotherapy–facilitated fertility-sparing surgery in patients with cervical cancer

Dermenzhy T.V.¹, Svintsitsky V.S.¹, Svintsitska A.V.¹, Taran L.M.¹, Klimova V.V.², Stepanenko S.V.¹

• ¹Nonprofit Organization National Cancer Institute, Kyiv, Ukraine
• ²P.L. Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine

Summary. Cervical cancer is a clinically challenging condition requiring a balance between oncologic safety and fertility preservation. Objective. To present a clinical case of cervical cancer with fertility-sparing management. Case presentation. A 24-year-old woman was diagnosed with invasive HPV-associated squamous cell carcinoma of the cervix. Treatment and outcome. The patient received neoadjuvant chemotherapy followed by fertility-sparing surgery with no evidence of recurrence. Conclusions. An individualized multidisciplinary approach may provide favorable oncologic outcomes while preserving fertility.

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